The first detailed studies of the so-called P.1 variant show how it spread in the Amazonian city of Manaus. Here’s the latest Covid-19 news. More

As coronavirus cases fall, states are rescinding mask mandates and reopening businesses and schools, prompting people to emerge after months of isolation despite uncertainty about the pandemic’s future. More

A world divided between the vaccinated and unvaccinated promises relief for economies and families, but the ethical and practical risks are high. More

A defeat for President Biden, the decision was made as it became clear Neera Tanden didn’t have enough Democratic support. Here’s the latest in politics. More

President Biden and top Democrats are working to ensure that frustration over the exclusion of the minimum wage increase in the stimulus plan does not overshadow the success of the package. More

The action came as the administration declassified an intelligence finding that the F.S.B., one of Russia’s leading intelligence agencies, was responsible for the poisoning of Aleksei A. Navalny. More

Christopher A. Wray condemned the Capitol riot and told the Senate Judiciary Committee that agents had opened 2,000 domestic terrorism inquiries in recent years. More

The court also signaled that it could tighten the standards for using the Voting Rights Act to challenge all kinds of voting restrictions. More

As jockeying begins for 2024, rank-and-file Republicans say they are most drawn to leaders who both pledge fealty to the former president and appear to showcase a distinct political identity. More

Gov. Andrew Cuomo faced more calls for his resignation, and a Republican congressman and Trump backer, Lee Zeldin, said he was exploring a challenge to him next year. More

Mexico’s president has stood by a candidate accused of sexual assault. The case is testing the president’s promises of justice and equality for all. More

A truck slammed into an S.U.V. crowded with 25 people in an agricultural region where migrant smuggling is common. More

The collision of an S.U.V. and a tractor-trailer on the outskirts of Holtville, Calif., left at least 13 people dead. More

A priest who was hospitalized last year with Covid-19 offered funeral Masses for two victims. More

Long hailed for his bravery during the 1994 Rwandan genocide, Paul Rusesabagina is now charged with being an insurgent leader. Did Rwanda change, or did he? More